Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329333 | 0.84 | NPY1R (0.43) | NPY1RNPY2RSLC6A4HTR6 | |
| SCHEMBL29333349 | 0.83 | NPY1R (0.43) | NPY1RNPY2RSLC6A4HTR6 | |
| SCHEMBL20562112 | 0.81 | NPY1R (0.42) | NPY1RNPY2RTSHRKDM4EMEN1 | |
| SCHEMBL8229273 | 0.79 | GAA (0.44) | POLBTSHRSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL31053234 | 0.79 | NPY1R (0.44) | NPY1RNPY2RPOLBTSHRSMN1; SMN2 | |
| SCHEMBL27647596 | 0.78 | NPY1R (0.44) | NPY1RNPY2RPOLBTSHRLMNA | |
| SCHEMBL24329334 | 0.77 | NPY1R (0.42) | NPY1RNPY2RSLC6A4HTR6 | |
| SCHEMBL20833810 | 0.77 | NPY1R (0.42) | NPY1RNPY2RSLC6A4HTR6KDM4E | |
| SCHEMBL3484403 | 0.76 | PYCR1 (0.53) | TSHRSMN1; SMN2L3MBTL1KDM4EMEN1 | |
| SCHEMBL8237277 | 0.76 | CREBBP (0.45) | LMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |