Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130860 | 0.88 | KDM4E (0.57) | MEN1KMT2AHTTPIK3CANOD1 | |
| SCHEMBL14247557 | 0.83 | NPC1 (0.50) | MEN1KMT2AHTTPIK3CANOD1 | |
| SCHEMBL9556044 | 0.82 | MEN1 (0.47) | MEN1KMT2AHTTNOD1DYRK1A | |
| SCHEMBL1704422 | 0.80 | KDM4E (0.46) | MEN1KMT2AHTTMAPTNPC1 | |
| SCHEMBL2175321 | 0.79 | RAB9A (0.69) | MEN1KMT2AHTTNOD1POLB | |
| SCHEMBL23638514 | 0.75 | NPC1 (0.57) | KMT2APOLBMAPTTP53NPC1 | |
| SCHEMBL2625546 | 0.74 | MCHR1 (0.43) | MEN1KMT2AHTTMAPTNPC1 | |
| SCHEMBL15000607 | 0.74 | NPC1 (0.57) | MEN1KMT2APOLBMAPTTP53 | |
| SCHEMBL25171869 | 0.74 | DYRK1A (0.50) | MEN1KMT2AHTTPIK3CADYRK1A | |
| SCHEMBL31220083 | 0.74 | DYRK1A (0.50) | MEN1KMT2AHTTPIK3CADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |