Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575974 | 0.82 | LMNA (0.87) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL31276967 | 0.79 | CDK1 (0.82) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL17595823 | 0.77 | LMNA (0.79) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL19328343 | 0.77 | CA1 (0.65) | LMNAGAAALDH1A1KMT2AMAPT | |
| SCHEMBL10786460 | 0.76 | LMNA (0.82) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL11797289 | 0.71 | LMNA (0.68) | LMNAGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL14574192 | 0.71 | CDK1 (0.63) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL11772198 | 0.71 | CDK1 (0.63) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL11206964 | 0.71 | CDK1 (0.68) | LMNAGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL13886027 | 0.71 | CYP1A2 (0.72) | LMNAGAAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116782903-A | Substituted pyridone compounds and uses thereof | 南京再明医药有限公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |