Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308791 | 0.84 | CA1 (0.65) | CA1CA2LMNAALDH1A1KMT2A | |
| SCHEMBL24329888 | 0.77 | LMNA (0.67) | IDO1GPR174LMNAALDH1A1KMT2A | |
| SCHEMBL23121013 | 0.75 | POLB (0.59) | CA1CA2ALDH1A1KMT2AMAPT | |
| SCHEMBL11672644 | 0.75 | CA1 (0.68) | CA1CA2ABATLMNAALDH1A1 | |
| SCHEMBL7390323 | 0.75 | ITGB3 (0.76) | CA1CA2ITGB3ITGA2B | |
| SCHEMBL7822000 | 0.74 | CYP1A1 (0.70) | CA1CA2ALDH1A1KMT2AMAPT | |
| SCHEMBL11519940 | 0.73 | ALDH1A1 (0.67) | CA1CA2ABATLMNAALDH1A1 | |
| SCHEMBL7390331 | 0.73 | CA2 (0.58) | CA1CA2ABATLMNAALDH1A1 | |
| SCHEMBL3451684 | 0.73 | LMNA (0.64) | IDO1LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL8879067 | 0.73 | CA1 (0.61) | CA1CA2FOLH1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-09-25 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | UGDH, GALE, UGGT1 | CA1 4286/4885CA2 3372/4885IDO1 190/4885 |
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | UGDH, GALE, UGGT1 | CA1 4286/4885CA2 3372/4885IDO1 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.