Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.87 |
| ▸ | GAA | P10253 | 5/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17595823 | 0.95 | LMNA (0.79) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL5138189 | 0.89 | KMT2A (0.73) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL8956279 | 0.86 | KMT2A (0.78) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL15224205 | 0.84 | KMT2A (0.68) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL3958934 | 0.84 | KMT2A (0.80) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL4397577 | 0.83 | ALDH1A1 (0.83) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL11438307 | 0.82 | KMT2A (0.77) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL7215016 | 0.82 | KMT2A (0.66) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL24329888 | 0.82 | LMNA (0.67) | LMNAGAAALDH1A1HPGDKMT2A | |
| SCHEMBL3013357 | 0.81 | KMT2A (0.64) | LMNAGAAALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080658-A | Single-molecule difunctional organic catalyst and preparation method and application thereof | 浙江大学 | 2024-12-06 | — | — | CN | disclosed |
| US-10633403-B2 | N-heterocyclic phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2020-04-28 | — | — | US | disclosed |
| US-10633403-B2 | N-heterocyclic phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
| WO-2016040479-A1 | N-HETEROCYCLIC PHOSPHINES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2016-03-17 | — | — | WO | disclosed |
| US-8653259-B2 | Process for synthesizing heterocyclic compounds | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-02-18 | — | — | US | disclosed |
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| CN-1795178-A | Process for synthesizing heterocyclic compounds | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-06-28 | — | — | CN | disclosed |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| US-4713382-A | N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents | SYNTEX (U.S.A.) INC. (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0204265-A1 | N-Phenyl-4-phenyl-1-piperazine carboxamidines and related compounds as antiarrhythmic agents | LABORATOIRES SYNTEX S.A. (FR) | 1986-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | LMNA 3601/4885GAA 4181/4885ALDH1A1 4621/4885 |
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | TST, NISCH, CLIC4 | LMNA 4395/4885GAA 1126/4885ALDH1A1 406/4885 |
| US-10633403-B2 | N-heterocyclic phosphines | NANP, PPIP5K2, PHPT1 | LMNA 3601/4885GAA 4181/4885ALDH1A1 4621/4885 |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | TST, NISCH, CLIC4 | LMNA 4220/4885GAA 1253/4885ALDH1A1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.