Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.57 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321057 | 1.00 | CYP11B1 (0.57) | CYP11B1CYP11B2HCAR1PI4KAPI4K2B | |
| SCHEMBL24345252 | 0.90 | CYP11B1 (0.48) | CYP11B1CYP11B2HCAR1PI4KAPI4K2B | |
| SCHEMBL15353266 | 0.74 | CDK4 (0.38) | CYP11B1CYP11B2HCAR1PI4KAPI4K2B | |
| SCHEMBL2546299 | 0.73 | CYP11B1 (0.54) | CYP11B1CYP11B2SMN1; SMN2TDP1HTT | |
| SCHEMBL27934023 | 0.70 | MAPK1 (0.44) | CYP11B1CYP11B2SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL22159521 | 0.69 | HTT (0.46) | CYP11B1CYP11B2DDB1CRBNIKZF3 | |
| SCHEMBL2194142 | 0.69 | HCAR1 (0.50) | CYP11B1CYP11B2HCAR1PI4KAPI4K2B | |
| Amantadine SCHEMBL6561833 | 0.68 | CYP11B1 (0.48) | CYP11B1CYP11B2DDB1CRBNIKZF3 | |
| SCHEMBL24783187 | 0.68 | DDB1 (0.49) | CYP11B1CYP11B2HCAR1DDB1CRBN | |
| SCHEMBL10668441 | 0.68 | PI4KA (0.55) | CYP11B1CYP11B2HCAR1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691135-B2 | Synthesis of alkynones via carbonylative Sonogashira coupling reactions catalyzed by Pd(II)-N-Heterocyclic carbene-pyridine complexes | KING FAHD UNIVERSITY OF PETROLEUM & MINERALS (SA) | 2023-07-04 | — | — | US | disclosed |
| WO-2022081953-A1 | SYNTHESIS OF ALKYNONES VIA CARBONYLATIVE SONOGASHIRA COUPLING REACTIONS CATALYZED BY PD(II)-N-HETEROCYCLIC CARBENE-PYRIDINE COMPLEXES | SAUDI ARABIAN OIL COMPANY (SA) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691135-B2 | Synthesis of alkynones via carbonylative Sonogashira coupling reactions catalyzed by Pd(II)-N-Heterocyclic carbene-pyridine complexes | PDK2, SNCA, YAP1 | CYP11B1 978/4885CYP11B2 273/4885HCAR1 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.