Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321057 | 0.73 | CYP11B1 (0.57) | CYP11B1CYP11B2TDP1HTTLMNA | |
| SCHEMBL24329965 | 0.73 | CYP11B1 (0.57) | CYP11B1CYP11B2TDP1HTTLMNA | |
| SCHEMBL15022038 | 0.70 | TDP1 (0.52) | CYP11B1CYP11B2HPGDALOX15HSD17B10 | |
| SCHEMBL1800353 | 0.68 | TDP1 (0.48) | CYP11B1CYP11B2HPGDALOX15HSD17B10 | |
| SCHEMBL1488096 | 0.68 | TDP1 (0.48) | CYP11B1CYP11B2HPGDALOX15HSD17B10 | |
| Amantadine SCHEMBL6561833 | 0.65 | CYP11B1 (0.48) | CYP11B1CYP11B2USP2TDP1HTT | |
| SCHEMBL239691 | 0.65 | HTT (0.48) | CYP11B1CYP11B2HPGDALOX15HSD17B10 | |
| SCHEMBL24345252 | 0.65 | CYP11B1 (0.48) | CYP11B1CYP11B2HPGDHSD17B10TDP1 | |
| SCHEMBL15401045 | 0.64 | TDP1 (0.48) | CYP11B1CYP11B2ALOX15HSD17B10TDP1 | |
| SCHEMBL8590777 | 0.64 | HSD17B10 (0.49) | CYP11B1CYP11B2HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263566-A1 | 7-Hydroxy-benzoimidazole-4-yl-methanone Derivatives and PBK Inhibitors Containing the Same | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263566-A1 | 7-Hydroxy-benzoimidazole-4-yl-methanone Derivatives and PBK Inhibitors Containing the Same | PDXK, BCKDK, SBK1 | CYP11B1 778/4885CYP11B2 724/4885HPGD 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.