Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330862 | 0.87 | F10 (0.31) | — | |
| SCHEMBL24299252 | 0.81 | CYP1A2 (0.40) | L3MBTL1 | |
| SCHEMBL24298907 | 0.81 | PARP1 (0.38) | SYK | |
| SCHEMBL24326765 | 0.79 | TDP1 (0.43) | PLK1NUDT1 | |
| SCHEMBL24325812 | 0.74 | MAP4K1 (0.39) | PLK1SYK | |
| SCHEMBL24310515 | 0.73 | — | — | |
| SCHEMBL24326357 | 0.71 | HPGD (0.41) | KDM4EMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL22509298 | 0.69 | CYP1A2 (0.40) | — | |
| SCHEMBL24326363 | 0.67 | TDP1 (0.46) | NUDT1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL24331435 | 0.65 | HSP90AA1 (0.50) | NUDT1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076626-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |