Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329987 | 0.87 | PLK1 (0.35) | — | |
| SCHEMBL24298907 | 0.79 | PARP1 (0.38) | LCK | |
| SCHEMBL24299252 | 0.79 | CYP1A2 (0.40) | — | |
| SCHEMBL24325812 | 0.72 | MAP4K1 (0.39) | F10LCK | |
| SCHEMBL24310515 | 0.71 | — | — | |
| SCHEMBL24326765 | 0.71 | TDP1 (0.43) | HTR7 | |
| SCHEMBL24331843 | 0.70 | NR1H2 (0.34) | — | |
| SCHEMBL22509298 | 0.67 | CYP1A2 (0.40) | — | |
| SCHEMBL24310313 | 0.66 | SRC (0.30) | — | |
| SCHEMBL24310507 | 0.65 | AGTR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076626-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |