Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23798302 | 0.88 | KISS1R (0.42) | CNR1LMNAPKMALDH1A1HPGD | |
| SCHEMBL14414544 | 0.84 | CA1 (0.40) | CNR1LMNAPKMALDH1A1KMT2A | |
| SCHEMBL24098231 | 0.84 | ALDH1A1 (0.42) | CNR1LMNAPKMALDH1A1HPGD | |
| SCHEMBL13311543 | 0.81 | CA1 (0.46) | ALDH1A1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL22134299 | 0.81 | CNR1 (0.44) | CNR1LMNAPKMANPEPRNPEP | |
| SCHEMBL13703456 | 0.81 | ANPEP (0.46) | CNR1LMNAPKMANPEPRNPEP | |
| SCHEMBL7257878 | 0.79 | ALDH1A1 (0.58) | CNR1LMNAPKMANPEPRNPEP | |
| SCHEMBL23589880 | 0.79 | ANPEP (0.44) | CNR1LMNAPKMANPEPRNPEP | |
| SCHEMBL21235866 | 0.78 | CNR1 (0.45) | CNR1LMNAPKMANPEPRNPEP | |
| SCHEMBL11452609 | 0.77 | ALDH1A1 (0.61) | CNR1LMNAPKMANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081928-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |