Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23589880 | 0.78 | ANPEP (0.44) | CNR1LMNAKMT2APKMANPEP | |
| SCHEMBL24330010 | 0.78 | CNR1 (0.45) | CNR1LMNAKMT2APKMANPEP | |
| SCHEMBL19033460 | 0.78 | LMNA (0.40) | CNR1LMNAKMT2AADH1BADH1C | |
| SCHEMBL22134299 | 0.76 | CNR1 (0.44) | CNR1LMNAKMT2APKMANPEP | |
| SCHEMBL13703456 | 0.76 | ANPEP (0.46) | CNR1LMNAKMT2APKMANPEP | |
| SCHEMBL24465216 | 0.76 | LMNA (0.47) | LMNAKMT2AADH1BADH1CADH1A | |
| SCHEMBL13227429 | 0.75 | LMNA (0.50) | CNR1LMNAKMT2AHPGDALDH1A1 | |
| SCHEMBL7257878 | 0.74 | ALDH1A1 (0.58) | CNR1LMNAPKMANPEPRNPEP | |
| SCHEMBL19114217 | 0.74 | ADH1B (0.56) | CNR1LMNAKMT2AADH1BADH1C | |
| SCHEMBL30520938 | 0.74 | ADH1B (0.48) | CNR1LMNAKMT2AADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019151133-A1 | MANUFACTURING METHOD FOR BORTEZOMIB CRYSTALS | 日本化薬株式会社 | 2019-08-08 | — | — | WO | disclosed |