Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329944 | 0.81 | NPC1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL13604061 | 0.80 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL24329871 | 0.80 | MAPT (0.45) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL13060358 | 0.80 | PPARG (0.36) | NPC1RAB9ASMN1; SMN2GAALMNA | |
| SCHEMBL13604063 | 0.78 | SMN1; SMN2 (0.50) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2929122 | 0.75 | MAPT (0.66) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL5206474 | 0.74 | MAPT (0.64) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL5008245 | 0.74 | MAPT (0.64) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL22606671 | 0.72 | ALOX15 (0.53) | MAPTNPC1RAB9APPARGHDAC6 | |
| SCHEMBL10281995 | 0.71 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |