Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | AOC2 | O75106 | 1/20 | 0.50 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77384 | 0.84 | ALDH1A1 (0.76) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL7945435 | 0.84 | GAA (0.59) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL20285376 | 0.84 | HDAC8 (0.65) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL1904111 | 0.81 | ALDH1A1 (0.70) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL18025237 | 0.79 | HDAC8 (0.69) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL21841727 | 0.79 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL1659983 | 0.78 | GAA (0.54) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| Propanol SCHEMBL28827183 | 0.78 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL317796 | 0.77 | CA12 (0.52) | KDM4EALDH1A1GAAKMT2AHSD17B10 | |
| SCHEMBL18448812 | 0.77 | ALDH1A1 (0.66) | KDM4EALDH1A1GAAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382947-A1 | METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2023-11-30 | — | — | US | disclosed |
| WO-2022079127-A1 | METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382947-A1 | METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT | DCLRE1A, CNBP, RNGTT | KDM4E 4631/4885ALDH1A1 3895/4885GAA 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.