Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | AOC2 | O75106 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662977 | 0.86 | OGG1 (0.55) | KMT2AALDH1A1KDM4EAOC2LMNA | |
| SCHEMBL77384 | 0.80 | ALDH1A1 (0.76) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL24331925 | 0.78 | KDM4E (0.58) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1904111 | 0.77 | ALDH1A1 (0.70) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL18025237 | 0.75 | HDAC8 (0.69) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL21841727 | 0.75 | ALDH1A1 (0.58) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL12731305 | 0.74 | ASF1A (0.66) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL12799520 | 0.74 | ASF1A (0.66) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| Propanol SCHEMBL28827183 | 0.74 | ALDH1A1 (0.61) | GAAKMT2AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL18448812 | 0.73 | ALDH1A1 (0.66) | GAAKMT2AHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488021-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | Dow AgroSciences LLC (US) | 2012-08-22 | — | — | EP | claimed |
| WO-2011047025-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2011-04-21 | — | — | WO | claimed |
| US-20110086761-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2011-04-14 | — | — | US | claimed |
| EP-2488021-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | Dow AgroSciences LLC (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011047025-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2011-04-21 | — | — | WO | disclosed |
| US-20110086761-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086761-A1 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS | ERG28, DPM1, BROX | GAA 225/4885KMT2A 1411/4885HSD17B10 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.