Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24331950 | 0.84 | MAOA (0.39) | APPCLK1DYRK1ADYRK1BESR1 | |
| SCHEMBL24332270 | 0.84 | APP (0.38) | APPCLK1DYRK1ADYRK1BESR1 | |
| SCHEMBL13299953 | 0.78 | ESR1 (0.44) | APPESR1ESR2HDAC6HDAC1 | |
| SCHEMBL24332576 | 0.78 | APP (0.53) | APPESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL28829819 | 0.76 | APP (0.62) | APPESR1ESR2HDAC6HDAC1 | |
| SCHEMBL24017200 | 0.73 | MMP3 (0.58) | CYP11B2MMP3CA1CA2CA9 | |
| SCHEMBL11429055 | 0.71 | IMPDH2 (0.40) | APPCLK1DYRK1ADYRK1BCYP11B1 | |
| SCHEMBL11846382 | 0.70 | TTR (0.48) | CLK1DYRK1ADYRK1BHDAC6HDAC1 | |
| SCHEMBL34471251 | 0.69 | CYP2A6 (0.40) | APPCLK1DYRK1ADYRK1BCYP11B1 | |
| SCHEMBL18935941 | 0.69 | IMPDH2 (0.39) | APPCLK1DYRK1ADYRK1BCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080696-A1 | HIGH-REFRACTIVE-INDEX BENZAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 랩토 | 2022-04-21 | — | — | WO | disclosed |