Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734910 | 0.78 | MMP1 (0.48) | HRH3MMP1MMP9MMP3CACNA1G | |
| SCHEMBL20734861 | 0.77 | FFAR1 (0.44) | GLANPSR1 | |
| SCHEMBL20734860 | 0.77 | FFAR1 (0.44) | GLANPSR1 | |
| SCHEMBL20734814 | 0.75 | HPGD (0.40) | GLANPSR1MMP1MMP9MMP3 | |
| SCHEMBL20734875 | 0.74 | ALDH1A1 (0.41) | MMP1MMP9MMP3 | |
| SCHEMBL24333180 | 0.74 | HTT (0.41) | GLANPSR1 | |
| SCHEMBL20734813 | 0.74 | ALDH1A1 (0.41) | MMP1MMP9MMP3 | |
| SCHEMBL20734918 | 0.72 | AKR1B1 (0.42) | MMP1MMP9MMP3 | |
| SCHEMBL20734917 | 0.72 | AKR1B1 (0.42) | MMP1MMP9MMP3 | |
| SCHEMBL24333201 | 0.69 | TACR2 (0.32) | MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647306-B1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND AND PREPARATION METHOD THEREFOR | BEIJING JOEKAI BIOTECH LLC (CN) | 2022-04-06 | — | — | EP | disclosed |