Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 6/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734910 | 0.87 | MMP1 (0.48) | NPC1RAB9ATDP1MMP1MMP3 | |
| SCHEMBL20734861 | 0.86 | FFAR1 (0.44) | APPGLANPSR1ALDH1A1MAPT | |
| SCHEMBL20734860 | 0.86 | FFAR1 (0.44) | APPGLANPSR1ALDH1A1MAPT | |
| SCHEMBL24333180 | 0.83 | HTT (0.41) | NPC1RAB9AAPPGLANPSR1 | |
| SCHEMBL20734813 | 0.83 | ALDH1A1 (0.41) | NPC1RAB9AAPPMMP1MMP3 | |
| SCHEMBL20734875 | 0.83 | ALDH1A1 (0.41) | NPC1RAB9AAPPMMP1MMP3 | |
| SCHEMBL20735109 | 0.81 | HTT (0.33) | HPGDHTTMEN1KMT2AKDM4C | |
| SCHEMBL20734917 | 0.76 | AKR1B1 (0.42) | HPGDTDP1PTPN1MMP1MMP3 | |
| SCHEMBL21929341 | 0.75 | MAOB (0.48) | NPC1RAB9AMMP1MMP3MMP9 | |
| SCHEMBL24333352 | 0.75 | GLA (0.34) | GLANPSR1MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019029273-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京卓凯生物技术有限公司 | 2019-02-14 | — | — | WO | disclosed |
| WO-2019029274-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND AND PREPARATION METHOD THEREFOR | 北京卓凯生物技术有限公司 | 2019-02-14 | — | — | WO | disclosed |