Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24333731 | 0.87 | CHRM2 (0.37) | CHRM2CHRM1MAPK1MCHR1KCNH2 | |
| SCHEMBL24333739 | 0.84 | HTR7 (0.36) | CHRM2CHRM1MCHR1KCNH2TP53 | |
| SCHEMBL24334448 | 0.83 | CCR3 (0.32) | — | |
| SCHEMBL29469717 | 0.82 | ALOX5AP (0.36) | CHRM2CHRM1MEN1ALDH1A1KMT2A | |
| SCHEMBL24334359 | 0.82 | ALOX5AP (0.36) | CHRM2CHRM1MEN1ALDH1A1KMT2A | |
| SCHEMBL24334358 | 0.81 | ALDH1A1 (0.36) | TP53MEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL24333729 | 0.78 | HPGD (0.39) | CHRM2CHRM1MCHR1KCNH2MEN1 | |
| SCHEMBL29469819 | 0.78 | HPGD (0.39) | CHRM2CHRM1MCHR1KCNH2MEN1 | |
| SCHEMBL24334197 | 0.77 | MCL1 (0.35) | CHRM2CHRM1MEN1ALDH1A1KMT2A | |
| SCHEMBL29469829 | 0.77 | MCL1 (0.35) | CHRM2CHRM1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |