Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 9/20 | 0.36 |
| ▸ | FEN1 | P39748 | 9/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469717 | 1.00 | ALOX5AP (0.36) | ALOX5APFEN1PTGER4KDM4EMEN1 | |
| SCHEMBL24333729 | 0.88 | HPGD (0.39) | PTGER4KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL29469819 | 0.88 | HPGD (0.39) | PTGER4KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL29469812 | 0.85 | ALOX5AP (0.37) | ALOX5APFEN1PTGER4KDM4EMEN1 | |
| SCHEMBL24333951 | 0.85 | ALOX5AP (0.37) | ALOX5APFEN1PTGER4KDM4EMEN1 | |
| SCHEMBL24333740 | 0.84 | TP53 (0.37) | MEN1ALDH1A1GAAHPGDKMT2A | |
| SCHEMBL29469902 | 0.84 | TP53 (0.37) | MEN1ALDH1A1GAAHPGDKMT2A | |
| SCHEMBL24334447 | 0.83 | AGTR2 (0.37) | ALOX5APFEN1PTGER4KDM4EMEN1 | |
| SCHEMBL29469611 | 0.83 | AGTR2 (0.37) | ALOX5APFEN1PTGER4KDM4EMEN1 | |
| SCHEMBL24334356 | 0.82 | CHRM2 (0.34) | MEN1ALDH1A1KMT2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |