SCHEMBL24337058

SCHEMBL24337058

CNC1CC(C)N(c2ccc(-c3ccccc3P(C)(C)=O)c(F)c2F)C1=O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 0.65
FPR1 P21462 17/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22320943 0.89 FPR2 (0.70) FPR2FPR1
SCHEMBL25868522 0.86 FPR2 (0.56) FPR2FPR1
Hydrochloric Acid SCHEMBL30832920 0.85 FPR2 (0.56) FPR2FPR1
Hydrochloric Acid SCHEMBL21314763 0.85 FPR2 (0.56) FPR2FPR1
SCHEMBL21319266 0.84 FPR2 (0.65) FPR2FPR1
SCHEMBL24337033 0.84 FPR2 (0.65) FPR2FPR1
SCHEMBL30832912 0.84 FPR2 (0.65) FPR2FPR1
SCHEMBL24093591 0.83 FPR2 (0.48) FPR2FPR1
SCHEMBL25868380 0.81 FPR1 (0.84) FPR2FPR1
SCHEMBL21319188 0.80 FPR1 (1.00) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3981767-A1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS Bristol-Myers Squibb Company (US) 2022-04-13 EP disclosed
US-9586978-B2 Anti-viral compounds ABBVIE INC. (US) 2017-03-07 US disclosed