Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369878 | 0.84 | PTGER4 (0.56) | PTGER4CNR1POLBMAPTCNR2 | |
| SCHEMBL27581126 | 0.83 | PTGER4 (0.51) | PTGER4CNR1POLBMAPTCNR2 | |
| SCHEMBL2433516 | 0.83 | KDM4E (0.45) | RIPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL14592697 | 0.81 | PTGER4 (0.51) | PTGER4CNR1POLBMAPTCNR2 | |
| SCHEMBL2435623 | 0.74 | NR1I2 (0.40) | PTGER4POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL2432642 | 0.74 | EPHB3 (0.54) | — | |
| SCHEMBL2433943 | 0.74 | MAPT (0.48) | POLBMAPT | |
| SCHEMBL2432847 | 0.74 | ITGB1 (0.46) | MAPTCNR2KDM4EALDH1A1MEN1 | |
| SCHEMBL3428359 | 0.73 | PTGER4 (0.66) | PTGER4CNR1POLBMAPTCNR2 | |
| SCHEMBL1219481 | 0.73 | PTGER4 (0.88) | PTGER4CNR1POLBCNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |