Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728850 | 0.98 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL12335991 | 0.85 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL21016157 | 0.84 | GAA (0.40) | L3MBTL1MEN1KMT2ATDP1GAA | |
| SCHEMBL12335994 | 0.82 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL19200319 | 0.82 | TSHR (0.49) | L3MBTL1ALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL19226236 | 0.80 | KMT2A (0.45) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL22292146 | 0.79 | MEN1 (0.38) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL19176972 | 0.79 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL20121989 | 0.78 | MEN1 (0.55) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL23080297 | 0.78 | MEN1 (0.55) | L3MBTL1MEN1KMT2ATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098214-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING FIBROSIS | YALE UNIVERSITY | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098214-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING FIBROSIS | DUSP5, DUSP4, DUSP6 | L3MBTL1 4137/4885MEN1 4048/4885KMT2A 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.