Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12335994 | 0.96 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL12335991 | 0.94 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL12335992 | 0.82 | GAA (0.40) | KMT2AGAA | |
| SCHEMBL12335993 | 0.82 | FAAH (0.35) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8379974 | 0.82 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL19432542 | 0.82 | ATM (0.39) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL22821468 | 0.81 | ALDH1A1 (0.38) | ALDH1A1DPP4HSD11B1 | |
| SCHEMBL1515195 | 0.80 | MEN1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL19728850 | 0.80 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL19176978 | 0.80 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | OPRL1, OPRM1, OPRD1 | L3MBTL1 3149/4885MEN1 4070/4885KMT2A 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.