Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340012 | 0.79 | KDM4E (0.35) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL24340009 | 0.77 | KDM4E (0.32) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL24340010 | 0.76 | KDM4E (0.33) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL24339666 | 0.73 | SMN1; SMN2 (0.33) | LMNA | |
| SCHEMBL31636809 | 0.67 | ALDH1A1 (0.46) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL24339611 | 0.64 | CYP1A2 (0.40) | KDM4ENPC1ALDH1A1MAPK1HTT | |
| SCHEMBL13017447 | 0.61 | L3MBTL1 (0.38) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL16926828 | 0.60 | MAPT (0.40) | KDM4ENPC1ALDH1A1LMNAGLA | |
| SCHEMBL3251456 | 0.60 | ALDH1A1 (0.41) | KDM4ENPC1ALDH1A1HTTRAB9A | |
| SCHEMBL19760999 | 0.60 | L3MBTL1 (0.36) | KDM4ENPC1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048684-A1 | JNK INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 武汉朗来科技发展有限公司 | 2022-03-10 | — | — | WO | disclosed |