Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340009 | 0.77 | KDM4E (0.32) | KDM4EALDH1A1HTTNPC1LMNA | |
| SCHEMBL24340487 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1HTTNPC1LMNA | |
| SCHEMBL12515514 | 0.72 | ALOX15 (0.33) | KDM4EALDH1A1NPC1GLAALOX15 | |
| SCHEMBL2035429 | 0.72 | ALOX15 (0.33) | KDM4EALDH1A1NPC1GLAALOX15 | |
| SCHEMBL16286354 | 0.72 | ALOX15 (0.33) | KDM4EALDH1A1NPC1GLAALOX15 | |
| SCHEMBL31381002 | 0.72 | MEN1 (0.34) | KDM4EALDH1A1HTTGLAALOX15 | |
| SCHEMBL15566093 | 0.71 | HASPIN (0.41) | ALDH1A1L3MBTL1HASPIN | |
| SCHEMBL15565804 | 0.71 | MEN1 (0.38) | KDM4EALDH1A1NPC1LMNAL3MBTL1 | |
| SCHEMBL31636809 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1HTTNPC1LMNA | |
| SCHEMBL15566652 | 0.68 | HASPIN (0.33) | HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048684-A1 | JNK INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 武汉朗来科技发展有限公司 | 2022-03-10 | — | — | WO | disclosed |