Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340768 | 0.93 | MAPT (0.46) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL26033083 | 0.86 | LOXL2 (0.46) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL25835831 | 0.74 | LOXL2 (0.56) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL25849724 | 0.72 | LMNA (0.45) | MAPTALDH1A1MEN1KMT2ALPAR1 | |
| SCHEMBL7669610 | 0.72 | ALDH1A1 (0.61) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL24340866 | 0.71 | CKS1B (0.43) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL28993944 | 0.67 | CA1 (0.80) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL23600 | 0.67 | CA1 (0.80) | MAPTCYP4A11CA1CA2TDP1 | |
| SCHEMBL457540 | 0.66 | ALDH1A1 (0.61) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL10273113 | 0.65 | LOXL2 (0.61) | MAPTCYP4A11CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |