Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344303 | 0.81 | IRAK4 (0.43) | CYP3A4LMNACYP1A2CYP2C19USP2 | |
| SCHEMBL29534716 | 0.81 | IRAK4 (0.43) | CYP3A4LMNACYP1A2CYP2C19USP2 | |
| SCHEMBL12261899 | 0.76 | YTHDC1 (0.39) | CYP3A4LMNACYP1A2CYP2C19USP2 | |
| SCHEMBL20375579 | 0.74 | CYP1A2 (0.44) | CYP3A4LMNACYP1A2CYP2C19USP2 | |
| SCHEMBL30923912 | 0.72 | BTK (0.42) | IRAK4EGFR | |
| SCHEMBL6796490 | 0.72 | PDPK1 (0.45) | LMNACYP1A2CYP2C19TSHRALDH1A1 | |
| SCHEMBL19004853 | 0.71 | IRAK4 (0.43) | CYP3A4LMNACYP1A2CYP2C19USP2 | |
| SCHEMBL27991639 | 0.70 | EGFR (0.59) | CYP3A4LMNACYP1A2CYP2D6EGFR | |
| SCHEMBL22897343 | 0.70 | EGFR (0.44) | CYP3A4LMNACYP1A2CYP2D6EGFR | |
| SCHEMBL25517459 | 0.69 | PDPK1 (0.34) | ALDH1A1CHRM4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |