Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437277 | 0.86 | ADRB2 (0.47) | ADRB2ADRB1ADRB3PPARGPPARA | |
| SCHEMBL6542904 | 0.82 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL9364192 | 0.81 | CYP3A4 (0.53) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 | |
| SCHEMBL10577148 | 0.81 | ADRB2 (0.45) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 | |
| Benzene SCHEMBL29140663 | 0.80 | CYP3A4 (0.59) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 | |
| SCHEMBL30625938 | 0.80 | ADRB2 (0.57) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 | |
| SCHEMBL2436356 | 0.79 | PPARA (0.50) | PPARGPPARACYP3A4ALDH1A1PTPN7 | |
| SCHEMBL27294341 | 0.79 | ADRB2 (0.62) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 | |
| SCHEMBL16372021 | 0.79 | CYP3A4 (0.61) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 | |
| SCHEMBL157805 | 0.79 | CYP3A4 (0.61) | ADRB2ADRB1ADRB3CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |