Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434754 | 0.86 | ADRB2 (0.47) | ADRB2ADRB1ADRB3CYP3A4PPARA | |
| SCHEMBL6543550 | 0.84 | PPARA (0.45) | CYP3A4FBP1PPARAPPARGKDM4E | |
| SCHEMBL2441559 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2436622 | 0.78 | AKR1C3 (0.50) | PPARAPPARGKDM4EKMT2A | |
| SCHEMBL9364192 | 0.78 | CYP3A4 (0.53) | ADRB2ADRB1ADRB3CYP3A4RHOA | |
| SCHEMBL10577148 | 0.78 | ADRB2 (0.45) | ADRB2ADRB1ADRB3CYP3A4KDM4E | |
| SCHEMBL30625938 | 0.77 | ADRB2 (0.57) | ADRB2ADRB1ADRB3CYP3A4KDM4E | |
| SCHEMBL27294341 | 0.76 | ADRB2 (0.62) | ADRB2ADRB1ADRB3CYP3A4KDM4E | |
| SCHEMBL157805 | 0.76 | CYP3A4 (0.61) | ADRB2ADRB1ADRB3CYP3A4RHOA | |
| SCHEMBL16372021 | 0.76 | CYP3A4 (0.61) | ADRB2ADRB1ADRB3CYP3A4RHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |