Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24163564 | 0.86 | — | — | |
| SCHEMBL5948644 | 0.83 | FDPS (0.32) | — | |
| SCHEMBL24126201 | 0.81 | DNM1 (0.30) | TSHR | |
| SCHEMBL5948592 | 0.79 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL7602462 | 0.79 | TSHR (0.38) | TSHR | |
| SCHEMBL23506982 | 0.76 | — | — | |
| SCHEMBL8493312 | 0.75 | — | — | |
| SCHEMBL21078039 | 0.75 | ALDH1A1 (0.41) | TSHR | |
| SCHEMBL29678115 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL21166557 | 0.74 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-A9 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2022-04-20 | — | — | EP | disclosed |