Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 7/20 | 0.43 |
| ▸ | SOD1 | P00441 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280709 | 0.90 | QPCT (0.52) | QPCTSOD1NPC1RAB9AATM | |
| SCHEMBL20280623 | 0.88 | QPCT (0.48) | TOP1QPCTSOD1NPC1RAB9A | |
| SCHEMBL24349579 | 0.88 | QPCT (0.41) | TOP1QPCTSOD1NPC1RAB9A | |
| SCHEMBL2539814 | 0.83 | SOD1 (0.57) | QPCTSOD1NPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL5191266 | 0.82 | SOD1 (0.56) | QPCTSOD1NPC1RAB9AATM | |
| SCHEMBL20280488 | 0.80 | MEN1 (0.34) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL20280485 | 0.77 | MEN1 (0.35) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL19923777 | 0.74 | QPCT (0.45) | QPCTSOD1NPC1RAB9AATM | |
| SCHEMBL5903394 | 0.73 | NPC1 (0.55) | QPCTSOD1NPC1RAB9AATM | |
| SCHEMBL20267791 | 0.72 | MAPT (0.36) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555069-B1 | NOVEL AZOMETHINE DIRECT DYES BEARING AT LEAST ONE CATIONIC CHARGE, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | OREAL (FR) | 2022-03-30 | — | — | EP | disclosed |