Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SOD1 | P00441 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 7/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539814 | 0.84 | SOD1 (0.57) | NPC1RAB9AATMSOD1MEN1 | |
| Hydrochloric Acid SCHEMBL5191266 | 0.83 | SOD1 (0.56) | NPC1RAB9AATMSOD1MEN1 | |
| SCHEMBL11495035 | 0.83 | SOD1 (0.67) | NPC1RAB9AATMSOD1MEN1 | |
| 3-Aminophenol SCHEMBL15793122 | 0.82 | QPCT (0.49) | NPC1RAB9AATMSOD1MEN1 | |
| SCHEMBL291484 | 0.80 | QPCT (0.54) | NPC1RAB9AATMSOD1MEN1 | |
| Hydrochloric Acid SCHEMBL19549172 | 0.79 | QPCT (0.53) | NPC1RAB9AATMSOD1MEN1 | |
| Hydrochloric Acid SCHEMBL4396866 | 0.79 | QPCT (0.53) | NPC1RAB9AATMSOD1MEN1 | |
| SCHEMBL5903400 | 0.79 | POLB (0.66) | NPC1RAB9AATMSOD1MEN1 | |
| SCHEMBL9984729 | 0.78 | EGFR (0.46) | SOD1MEN1KMT2AQPCTALDH1A1 | |
| SCHEMBL15793526 | 0.77 | QPCT (0.51) | NPC1RAB9AATMSOD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135047-B2 | M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-11-14 | — | — | US | claimed |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-01-26 | — | — | US | claimed |
| EP-1575538-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004058201-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| US-7135047-B2 | M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-11-14 | — | — | US | disclosed |
| US-7135047-B2 | M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-11-14 | — | — | US | disclosed |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-01-26 | — | — | US | disclosed |
| EP-1575538-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004058201-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | KRT18, VIM, TPM4 | NPC1 4754/4885RAB9A 4476/4885ATM 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.