Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349664 | 0.92 | IGF1R (0.47) | IGF1RPOLBTMEM97SIGMAR1FGFR1 | |
| SCHEMBL26550823 | 0.83 | USP2 (0.48) | USP2LMNATSHRALOX15KMT2A | |
| SCHEMBL24348471 | 0.80 | TMEM97 (0.46) | TMEM97SIGMAR1TYRO3MERTK | |
| SCHEMBL24349014 | 0.79 | TMEM97 (0.45) | TMEM97SIGMAR1 | |
| SCHEMBL24348328 | 0.78 | TMEM97 (0.46) | KMT2AMEN1HSD17B10TMEM97SIGMAR1 | |
| SCHEMBL24348476 | 0.77 | TMEM97 (0.46) | IGF1RTMEM97SIGMAR1 | |
| SCHEMBL24348989 | 0.74 | TMEM97 (0.44) | TMEM97SIGMAR1 | |
| SCHEMBL24349476 | 0.74 | TMEM97 (0.46) | LMNATSHRKMT2AMEN1TMEM97 | |
| SCHEMBL24348472 | 0.74 | PDE2A (0.46) | CCNT1TMEM97SIGMAR1 | |
| SCHEMBL24349021 | 0.72 | PRKAB2 (0.64) | CCNA2CDK2TMEM97SIGMAR1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230329236-A1 | HERBICIDAL PYRIMIDINE DERIVATIVES | MOA Technology Limited (GB) | 2023-10-19 | — | — | US | disclosed |
| WO-2022053803-A1 | HERBICIDAL PYRIMIDINE DERIVATIVES | MOA Technology Limited (GB) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230329236-A1 | HERBICIDAL PYRIMIDINE DERIVATIVES | DPYD, XDH, DHX35 | IGF1R 2444/4885USP2 2619/4885LMNA 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.