Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349323 | 0.93 | APEX1 (0.59) | APEX1KDM4ETDP1CDC25BTSHR | |
| SCHEMBL24349723 | 0.90 | APEX1 (0.60) | APEX1KDM4ETDP1CDC25BTSHR | |
| SCHEMBL24349727 | 0.83 | KDM4E (0.43) | APEX1KDM4ETDP1CDC25BTSHR | |
| SCHEMBL24350118 | 0.83 | APEX1 (0.69) | APEX1KDM4ETDP1CDC25BTSHR | |
| SCHEMBL24349728 | 0.82 | ALDH1A1 (0.40) | APEX1KDM4ETDP1HTTALDH1A1 | |
| SCHEMBL24349764 | 0.82 | CYP19A1 (0.40) | APEX1KDM4ETDP1TSHRHTT | |
| SCHEMBL24349770 | 0.80 | LMNA (0.41) | KDM4ETSHRHTTALDH1A1CYP1A2 | |
| SCHEMBL15691574 | 0.76 | APEX1 (0.86) | APEX1TDP1TSHRALDH1A1BLM | |
| SCHEMBL24349336 | 0.75 | ALDH1A1 (0.42) | APEX1KDM4ETDP1TSHRHTT | |
| SCHEMBL29153332 | 0.75 | APEX1 (0.49) | APEX1KDM4ECDC25BTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220081510-A1 | THERMOPLASTIC RESIN, OPTICAL FILM MADE THEREFROM, DIOL COMPOUND, DIESTER COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081510-A1 | THERMOPLASTIC RESIN, OPTICAL FILM MADE THEREFROM, DIOL COMPOUND, DIESTER COMPOUND | RTF1, RNF10, RAD51 | APEX1 2356/4885KDM4E 2174/4885TDP1 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.