Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23346997 | 0.83 | KDM4E (0.42) | CASP6GAAPDCD1LG2CD274CYP2D6 | |
| SCHEMBL24312483 | 0.82 | CYP2D6 (0.43) | CASP6CYP2D6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL24352278 | 0.81 | CASP6 (0.40) | CASP6CD274CYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL30172379 | 0.78 | KCNA5 (0.44) | GAAPDCD1LG2CD274CYP2D6TSHR | |
| SCHEMBL27897863 | 0.77 | CYP2D6 (0.48) | CASP6CYP2D6CYP1A2ALDH1A1HSD17B10 | |
| Bromide SCHEMBL30172419 | 0.76 | KCNA5 (0.43) | GAAPDCD1LG2CD274CYP2D6TSHR | |
| SCHEMBL7503631 | 0.76 | CASP6 (0.42) | CASP6CD274CYP2D6CYP1A2CCNT1 | |
| SCHEMBL24312484 | 0.76 | DPP4 (0.46) | CASP6CYP2D6CYP1A2CLK4 | |
| SCHEMBL24352211 | 0.76 | CASP6 (0.49) | CASP6GAAPDCD1LG2CD274CYP2D6 | |
| SCHEMBL28144739 | 0.76 | CASP6 (0.39) | CASP6CYP2D6CYP1A2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | CASP6 2981/4885GAA 172/4885PDCD1LG2 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.