SCHEMBL2435459

SCHEMBL2435459

O=[PH]1Oc2c(Cc3ccccc3)cc(Cc3ccccc3)cc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.38
PTPN2 P17706 2/20 0.38
PTPN6 P29350 2/20 0.38
BCL2 P10415 1/20 0.33
BCL2L1 Q07817 1/20 0.33
CALM1 P0DP23 1/20 0.33
ELANE P08246 2/20 0.31
CTRC Q99895 3/20 0.31
LMNA P02545 1/20 0.31
ALOX5 P09917 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2436919 0.89 PTPN1 (0.37) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL28376471 0.86 GPR55 (0.36) BCL2BCL2L1ELANECTRCGPR55
SCHEMBL30594714 0.86 GPR55 (0.36) BCL2BCL2L1ELANECTRCGPR55
SCHEMBL2435285 0.86 PTPN1 (0.37) PTPN1PTPN2PTPN6CALM1ELANE
SCHEMBL2436277 0.84 FEN1 (0.36) PTPN1BCL2BCL2L1CALM1ELANE
SCHEMBL30164963 0.84 FEN1 (0.36) PTPN1BCL2BCL2L1CALM1ELANE
SCHEMBL2437141 0.83 NPC1 (0.33)
SCHEMBL2434834 0.78 PTGDR2 (0.31) PTPN1
SCHEMBL2434200 0.77 IDH1 (0.37) PTPN1CALM1ELANELMNA
SCHEMBL2437838 0.74 ALDH1A1 (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
US-4086206-A FLAME RETARDANTS, DEHYDROCONDENSATION SANKO KAIHATSU KAGAKU KENKYOSHO (JA) 1978-04-25 US disclosed