Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.82 |
| ▸ | ESRRG | P62508 | 10/20 | 0.82 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.81 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.81 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.81 |
| ▸ | ESRRB | O95718 | 1/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.71 |
| ▸ | PDE1A | P54750 | 1/20 | 0.67 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.67 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539097 | 1.00 | ESR1 (0.82) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL5136332 | 0.96 | PSMB1 (0.89) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL5075819 | 0.96 | ESR1 (0.74) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL5075243 | 0.96 | ESR1 (0.74) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL5075011 | 0.96 | ESR1 (0.74) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL14530901 | 0.91 | ESR1 (0.78) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL20842056 | 0.90 | ESRRG (1.00) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL20842080 | 0.90 | ESRRG (1.00) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL17151967 | 0.90 | ESR1 (0.91) | ESR1ESRRGPSMB1PSMB5PSMB2 | |
| SCHEMBL7807876 | 0.90 | ESR1 (0.91) | ESR1ESRRGPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459936-B1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-04-27 | — | — | EP | disclosed |