SCHEMBL243558

SCHEMBL243558

C=CC(=O)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.63
AKR1C3 P42330 3/20 0.61
GAA P10253 2/20 0.52
MAPT P10636 1/20 0.52
ALDH1A1 P00352 4/20 0.50
ATM Q13315 3/20 0.48
CDC25B P30305 2/20 0.48
TDP1 Q9NUW8 3/20 0.48
MAPK1 P28482 1/20 0.48
NR4A1 P22736 1/20 0.47
ELANE P08246 1/20 0.45
CDC25A P30304 1/20 0.44
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540662 1.00 AKT1 (0.63) AKT1AKR1C3GAAMAPTALDH1A1
SCHEMBL10347642 0.85 AKT1 (0.61) AKT1MAPTALDH1A1TDP1MAPK1
SCHEMBL11599726 0.84 AKT1 (0.53) AKT1AKR1C3GAAMAPTALDH1A1
SCHEMBL8387506 0.84 AKT1 (0.53) AKT1AKR1C3GAAMAPTALDH1A1
Ethylene SCHEMBL27279241 0.83 AKR1C3 (0.77) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL700595 0.82 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL29447165 0.82 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1ATM
2-Benzoylbenzoic Acid SCHEMBL10486620 0.82 AKR1C3 (0.77) AKT1AKR1C3GAAMAPTALDH1A1
SCHEMBL30340452 0.82 AKT1 (0.61) AKT1AKR1C3GAAMAPTALDH1A1
SCHEMBL14918787 0.81 ALDH1A1 (0.64) AKT1AKR1C3MAPTALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9909036-B2 Pressure-sensitive adhesive composition and pressure-sensitive adhesive tape 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-06 US claimed
US-20170037284-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE 3M INNOVATIVE PROPERTIES COMPANY 2017-02-09 US claimed
US-9487676-B2 Pressure-sensitive adhesive composition and pressure-sensitive adhesive tape 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-11-08 US claimed
EP-2291480-B1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE 3M INNOVATIVE PROPERTIES CO (US) 2013-03-13 EP claimed
US-20110076492-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE 3M INNOVATIVE PROPERTIES COMPANY 2011-03-31 US claimed
EP-2291480-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE 3M Innovative Properties Company (US) 2011-03-09 EP claimed
WO-2009154856-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-23 WO claimed
WO-2026105750-A1 HOLDER FOR CELLS, METHOD FOR HOLDING FLOATING CELLS, AND METHOD FOR RECOVERING FLOATING CELLS 日産化学株式会社 2026-05-21 WO disclosed
US-12509608-B2 Biological material adhesion inhibitor NISSAN CHEMICAL CORPORATION (JP) 2025-12-30 US disclosed
US-12421631-B2 Additive for thermal production and reinforcement of carbon fiber, and carbon fiber prepared there from KOREA INSTITUTE OF CARBON CONVERGENCE TECHNOLOGY (KR) 2025-09-23 US disclosed
CN-119947819-A Osmotic vaporization membrane 日东电工株式会社 2025-05-06 CN disclosed
CN-119708919-A Curable inkjet composition for metal-containing substrate, solder resist, and inkjet recording method 柯尼卡美能达株式会社 2025-03-28 CN disclosed
CN-119173541-A Active energy ray-curable composition and cured product thereof DIC株式会社 2024-12-20 CN disclosed
WO-2002072368-A2 GRAPHICS-DISPLAYING SHEET 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-09-19 WO disclosed
US-6245922-B1 PREPARED BY REACTING AN ELECTROPHILIC 2-ALKENYL AZALACTONE WITH A NUCLEOPHILIC AROMATIC KETONE; CAN BE COPOLYMERIZED WITH ACRYLIC MONOMERS AND PHOTOACTIVATED BY ACTINIC RADIATION TO CROSSLINK THE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-06-12 US disclosed
EP-0837844-B1 ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING & MFG (US) 2000-04-05 EP disclosed
EP-0837844-A1 ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-29 EP disclosed
WO-1997005101-A1 ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-13 WO disclosed
WO-1997005100-A1 CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-13 WO disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509608-B2 Biological material adhesion inhibitor ICAM1, EPCAM, VCAM1 AKT1 1019/4885AKR1C3 2559/4885GAA 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.