Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359208 | 1.00 | CTSB (0.47) | CTSBCTSSCTSKGLI1EPHX1 | |
| SCHEMBL14366019 | 0.82 | CTSB (0.43) | CTSBCTSSCTSKGLI1EPHX1 | |
| SCHEMBL9005010 | 0.80 | CTSB (0.58) | CTSBCTSSCTSKGLI1EPHX1 | |
| SCHEMBL9005013 | 0.80 | CTSB (0.58) | CTSBCTSSCTSKGLI1EPHX1 | |
| SCHEMBL9005007 | 0.80 | CTSB (0.58) | CTSBCTSSCTSKGLI1EPHX1 | |
| SCHEMBL12449151 | 0.77 | CTSB (0.41) | CTSBCTSSCTSKGLI1PSEN1 | |
| SCHEMBL24127281 | 0.77 | CTSB (0.36) | CTSBCTSSCTSKGLI1 | |
| SCHEMBL13252221 | 0.77 | PSEN1 (0.38) | EPHX1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16056705 | 0.77 | ALDH1A1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15304541 | 0.77 | PSEN1 (0.38) | EPHX1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |