Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 2/20 | 0.40 |
| ▸ | ARG2 | P78540 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25540249 | 1.00 | HDAC8 (0.41) | HDAC8HDAC6HDAC1ARG1ARG2 | |
| SCHEMBL24359060 | 0.89 | HDAC8 (0.31) | HDAC8HDAC6HDAC1ARG1ARG2 | |
| SCHEMBL9283501 | 0.84 | HDAC8 (0.42) | HDAC8HDAC6HDAC1ARG1ARG2 | |
| SCHEMBL9284738 | 0.84 | HDAC8 (0.42) | HDAC8HDAC6HDAC1ARG1ARG2 | |
| SCHEMBL12788428 | 0.84 | HDAC8 (0.42) | HDAC8HDAC6HDAC1ARG1ARG2 | |
| SCHEMBL24731188 | 0.81 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL28858890 | 0.81 | ALDH1A1 (0.34) | HDAC8HDAC6HDAC1DRD2CASP3 | |
| SCHEMBL24359069 | 0.81 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL14922679 | 0.79 | ATM (0.40) | HRH3 | |
| SCHEMBL28283697 | 0.79 | ATM (0.40) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |