Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305362 | 1.00 | KMT2A (0.45) | KMT2AKDM4ECNR1CNR2TDP1 | |
| Cadaverine Tartrate SCHEMBL2322053 | 0.93 | KDM4E (0.42) | KMT2AKDM4ECNR1CNR2TDP1 | |
| SCHEMBL30874883 | 0.92 | KMT2A (0.45) | KMT2AKDM4ECNR1CNR2TDP1 | |
| SCHEMBL30874890 | 0.92 | KMT2A (0.45) | KMT2AKDM4ECNR1CNR2TDP1 | |
| SCHEMBL1818486 | 0.87 | ALDH1A1 (0.48) | KMT2AKDM4ECNR1CNR2ALDH1A1 | |
| SCHEMBL2032193 | 0.87 | ALDH1A1 (0.48) | KMT2AKDM4ECNR1CNR2ALDH1A1 | |
| SCHEMBL4848261 | 0.85 | KMT2A (0.43) | KMT2AKDM4ETDP1ALDH1A1ELANE | |
| SCHEMBL976837 | 0.85 | KMT2A (0.49) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL7313734 | 0.85 | KMT2A (0.49) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL19894171 | 0.81 | KMT2A (0.46) | KMT2AKDM4ETDP1DPP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529252-A | Prodrugs for sustained release of therapeutic agents and uses thereof | 重庆两江药物研发中心有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022083679-A1 | PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF | LIANGJIANG MEDICINE CO., LTD. (CN) | 2022-04-28 | — | — | WO | disclosed |