Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771389 | 0.88 | ALDH1A1 (0.46) | KDM4EACEALDH1A1SMN1; SMN2 | |
| SCHEMBL24359262 | 0.85 | KMT2A (0.45) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL7305362 | 0.85 | KMT2A (0.45) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL7313734 | 0.82 | KMT2A (0.49) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL976837 | 0.82 | KMT2A (0.49) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL13653651 | 0.80 | HTR1A (0.44) | KMT2AKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL19894171 | 0.79 | KMT2A (0.46) | KMT2AKDM4ETDP1DPP4POLB | |
| Cadaverine Tartrate SCHEMBL2322053 | 0.79 | KDM4E (0.42) | KMT2AKDM4ETDP1ELANEDPP4 | |
| SCHEMBL30874890 | 0.78 | KMT2A (0.45) | KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL30874883 | 0.78 | KMT2A (0.45) | KMT2AKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |