SCHEMBL24359263

SCHEMBL24359263

NCC1CCCN1C(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 11/20 0.42
OPRD1 P41143 11/20 0.42
OPRK1 P41145 11/20 0.42
OPRL1 P41146 11/20 0.42
L3MBTL3 Q96JM7 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
HIF1A Q16665 1/20 0.41
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3451288 0.83 KMT2A (0.46) OPRM1OPRD1OPRK1OPRL1L3MBTL3
SCHEMBL24359355 0.83 KMT2A (0.46) OPRM1OPRD1OPRK1OPRL1L3MBTL3
SCHEMBL9063099 0.83 L3MBTL3 (0.42) OPRM1OPRD1OPRK1OPRL1L3MBTL3
SCHEMBL11461803 0.82 SLC18A2 (0.45) CYP1A2CYP2D6HIF1A
SCHEMBL14458306 0.78 CYP1A2 (0.43) OPRM1OPRD1OPRK1OPRL1L3MBTL3
SCHEMBL6079285 0.78 DPP4 (0.41)
SCHEMBL4727655 0.77 KDM4E (0.41) OPRL1CYP1A2CYP2D6HIF1A
SCHEMBL2883224 0.77 KDM4E (0.41) OPRL1CYP1A2CYP2D6HIF1A
SCHEMBL29046165 0.77 CHRM3 (0.47) CYP1A2CYP2D6KMT2A
SCHEMBL24359261 0.76 KMT2A (0.48) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230391731-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2023-12-07 US disclosed
WO-2022083679-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391731-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF GRPR, SLC2A8, HPGDS OPRM1 1194/4885OPRD1 1921/4885OPRK1 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.