SCHEMBL24359261

SCHEMBL24359261

O=C(O)NCC1CCCN1C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45
CTSK P43235 1/20 0.45
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GLP1R P43220 1/20 0.42
HRH3 Q9Y5N1 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17114330 0.83 KMT2A (0.48) KMT2ARAB9ASMN1; SMN2GLP1RKDM4E
SCHEMBL17114329 0.83 KMT2A (0.48) KMT2ARAB9ASMN1; SMN2GLP1RKDM4E
SCHEMBL2888254 0.82 HCRTR1 (0.44) KMT2AKDM4E
SCHEMBL3451288 0.79 KMT2A (0.46) KMT2ACNR1CNR2MEN1KDM4E
SCHEMBL24359355 0.79 KMT2A (0.46) KMT2ACNR1CNR2MEN1KDM4E
SCHEMBL3293435 0.78 KMT2A (0.46) KMT2ASMN1; SMN2GLP1RHTT
SCHEMBL24359263 0.76 OPRM1 (0.42) KMT2A
SCHEMBL20608338 0.76 GLP1R (0.46) KMT2AGLP1RHTT
SCHEMBL19067213 0.76 GLP1R (0.46) KMT2AGLP1RHTT
SCHEMBL29046165 0.76 CHRM3 (0.47) KMT2ASMN1; SMN2NPSR1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230391731-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2023-12-07 US disclosed
CN-116529252-A Prodrugs for sustained release of therapeutic agents and uses thereof 重庆两江药物研发中心有限公司 2023-08-01 CN disclosed
WO-2022083679-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391731-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF GRPR, SLC2A8, HPGDS KMT2A 4380/4885CTSL 199/4885CTSB 472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.