SCHEMBL24359348

SCHEMBL24359348

O=COc1ccc(CC2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL3 Q96JM7 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GRIN2B Q13224 6/20 0.41
ADRA2A P08913 5/20 0.41
HTR2A P28223 5/20 0.41
ADRA1A P35348 5/20 0.41
GRIN1 Q05586 4/20 0.41
HTR2B P41595 4/20 0.41
SIGMAR1 Q99720 3/20 0.41
GRIN2D O15399 2/20 0.41
HTR1A P08908 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2C Q14957 2/20 0.41
LMNA P02545 1/20 0.41
ADRB1 P08588 1/20 0.41
DRD2 P14416 1/20 0.41
ADRA2B P18089 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24359362 0.83 DRD4 (0.54) HRH3MEN1KMT2AGRIN2BGRIN1
SCHEMBL24359363 0.79 GRIN2B (0.62) GRIN2BADRA2AHTR2AADRA1AGRIN1
SCHEMBL24359569 0.79 PRMT3 (0.50) MEN1KMT2AL3MBTL3L3MBTL1GRIN2B
SCHEMBL26911633 0.76 MEN1 (0.49) MEN1KMT2AL3MBTL3L3MBTL1GRIN2B
SCHEMBL29046166 0.75 CARM1 (0.47) MEN1KMT2AGRIN2BADRA2AHTR2A
SCHEMBL3630897 0.72 ALDH1A1 (0.52) MEN1KMT2AL3MBTL3L3MBTL1OPRK1
SCHEMBL13857882 0.71 ALDH1A1 (0.55) MEN1KMT2AL3MBTL3L3MBTL1OPRK1
SCHEMBL8478880 0.70 L3MBTL3 (0.48) MEN1KMT2AL3MBTL3L3MBTL1ADRA2A
SCHEMBL29046167 0.70 CCR3 (0.47) HRH3MEN1KMT2AKCNH2
SCHEMBL16226629 0.69 GRIN2B (0.58) MEN1KMT2AL3MBTL3L3MBTL1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022083679-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2022-04-28 WO disclosed