Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 15/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 15/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884654 | 0.81 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL1762438 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL1879120 | 0.74 | CYP11B2 (0.64) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL6540315 | 0.71 | PGR (0.49) | CYP11B1CYP11B2TDP2 | |
| SCHEMBL24335288 | 0.71 | CYP11B1 (0.43) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL4898332 | 0.70 | KIF11 (0.51) | CYP11B1CYP11B2TDP2 | |
| SCHEMBL748904 | 0.68 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL29849907 | 0.68 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL1883166 | 0.68 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL29849827 | 0.68 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2CYP2C9TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082305-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-04-28 | — | — | WO | disclosed |