Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359488 | 0.83 | EPHX1 (0.54) | TAAR1NR3C2FFAR1 | |
| SCHEMBL24359478 | 0.83 | FFAR1 (0.42) | TAAR1FFAR1MAOB | |
| SCHEMBL24359351 | 0.83 | NOS1 (0.50) | NOS1FFAR1 | |
| SCHEMBL2857831 | 0.82 | TAAR1 (0.58) | TAAR1NR3C2FFAR1CASP3CASP7 | |
| SCHEMBL30344632 | 0.82 | TAAR1 (0.58) | TAAR1NR3C2FFAR1CASP3CASP7 | |
| SCHEMBL2090292 | 0.81 | TAAR1 (0.56) | TAAR1NAAANR3C2FFAR1MAOB | |
| SCHEMBL24359377 | 0.76 | MAPT (0.53) | NOS1CASP3 | |
| SCHEMBL24359483 | 0.73 | NOS1 (0.53) | NOS1CASP3 | |
| SCHEMBL2761735 | 0.72 | MAPT (0.55) | NOS1 | |
| SCHEMBL376652 | 0.72 | MAPT (0.55) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087456-A1 | NEW COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |