Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30412030 | 0.85 | EPHX1 (0.59) | EPHX1TAAR1AURKANR3C2HDAC1 | |
| SCHEMBL249437 | 0.84 | EPHX1 (0.61) | EPHX1TAAR1AURKANR3C2HDAC1 | |
| SCHEMBL185922 | 0.84 | TAAR1 (0.62) | EPHX1TAAR1AURKANR3C2HDAC1 | |
| SCHEMBL30645023 | 0.84 | TAAR1 (0.62) | EPHX1TAAR1AURKANR3C2HDAC1 | |
| SCHEMBL24359482 | 0.83 | TAAR1 (0.47) | TAAR1NR3C2FFAR1 | |
| SCHEMBL4309679 | 0.82 | TAAR1 (0.60) | EPHX1TAAR1AURKANR3C2HDAC1 | |
| SCHEMBL24359351 | 0.80 | NOS1 (0.50) | HDAC1HDAC8FFAR1 | |
| SCHEMBL8491974 | 0.75 | TAAR1 (0.61) | EPHX1TAAR1NR3C2HDAC1HDAC8 | |
| SCHEMBL7150587 | 0.74 | MAPT (0.60) | EPHX1TAAR1HDAC1HDAC8FFAR1 | |
| SCHEMBL24359478 | 0.74 | FFAR1 (0.42) | EPHX1TAAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087456-A1 | NEW COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |