SCHEMBL24359593

SCHEMBL24359593

c1csc(-c2ccc(Sc3ccc4[nH]cnc4c3)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.38
TUBB P07437 2/20 0.38
TUBA3C P0DPH7 2/20 0.38
TUBA1B P68363 2/20 0.38
TUBA4A P68366 2/20 0.38
TUBB4B P68371 2/20 0.38
TUBB3 Q13509 2/20 0.38
TUBB2A Q13885 2/20 0.38
TUBB8 Q3ZCM7 2/20 0.38
TUBA3E Q6PEY2 2/20 0.38
TUBA1A Q71U36 2/20 0.38
TUBA1C Q9BQE3 2/20 0.38
TUBB6 Q9BUF5 2/20 0.38
TUBB2B Q9BVA1 2/20 0.38
TUBB1 Q9H4B7 2/20 0.38
HTR1D P28221 2/20 0.36
HTR1B P28222 2/20 0.36
CHEK1 O14757 1/20 0.36
SCD O00767 1/20 0.36
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2457552 0.84 HTR1D (0.45) HTR1DHTR1BCHEK1LTA4HCYP17A1
SCHEMBL2457857 0.76 QPCT (0.53) SCDQPCTLKCNH2NPC1RAB9A
SCHEMBL2542932 0.74 QPCT (0.50) HTR1DHTR1BLTA4HCYP17A1CYP11B1
SCHEMBL2542450 0.74 IP6K1 (0.43) LTA4HCYP17A1CYP11B1CYP11B2NPC1
SCHEMBL26041554 0.74 QPCT (0.44) CHEK1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL28154361 0.71 LTA4H (0.50) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL26911506 0.70 CHEK2 (0.38) CHEK1SCDNPC1RAB9AMAPT
SCHEMBL29600798 0.70 KCNH2 (0.67) LTA4HKCNH2
SCHEMBL24359561 0.70 KCNH2 (0.67) LTA4HKCNH2
SCHEMBL24359560 0.69 LMNA (0.60) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022086110-A1 THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF 고려대학교 산학협력단 2022-04-28 WO disclosed