Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17194935 | 0.81 | RAB9A (0.50) | BRD4PDK2KDM4ELMNARXFP1 | |
| SCHEMBL13712981 | 0.81 | RAB9A (0.48) | BRD4PDK2KDM4ELMNARXFP1 | |
| SCHEMBL24359874 | 0.77 | BRD4 (0.39) | BRD4PDK2KDM4ELMNARXFP1 | |
| SCHEMBL14650908 | 0.71 | GABRA1 (0.50) | LMNASMN1; SMN2HPGDKMT2ATSHR | |
| SCHEMBL11017758 | 0.70 | DPP4 (0.57) | PDK2 | |
| SCHEMBL14708718 | 0.68 | GABRA1 (0.43) | LMNAALDH1A1HPGDTSHR | |
| SCHEMBL20150088 | 0.68 | ALDH1A1 (0.50) | KDM4ERAB9AALDH1A1NPC1NPSR1 | |
| SCHEMBL9902022 | 0.67 | RAB9A (0.52) | BRD4PDK2KDM4ELMNARXFP1 | |
| SCHEMBL21091606 | 0.67 | RAB9A (0.57) | BRD4PDK2KDM4ELMNARAB9A | |
| SCHEMBL10034982 | 0.67 | RAB9A (0.80) | BRD4PDK2KDM4ERXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495358-B1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2022-04-27 | — | — | EP | disclosed |